Nursing Practice Today 2018. 5(1):222-227.

Insulin injection site and time interval administration for the postprandial glucose control in patient with diabetes type 2: A randomized clinical trial
Agus Santosa, Danong Erdiawan, Elsye-Maria Rosa


Background & Aim: This study aimed to determine the effects of insulin injection site and interval timing to the control of postprandial glucose in diabetes mellitus patients type 2.

Methods & Material: The study was an experimental with Randomized Complete Block Design (RCBD). The population were patients with diabetes mellitus type 2 in dr. Moewardi Hospital Solo, Central Java consisted of 60 respondents taken from simple random sampling and the respondents were divided into 4 blocks. Injection used was Rapid-acting insulin with the dosage prescribed by the doctor. Injection was done in four (4) locations; abdomen, deltoid, thigh and gluteus. The administration were 0 minutes (along with meals), 10 minutes before meal, 20 minutes before meal and 30 minutes before meal. Postprandial glucose levels were measured using a Glucometer. Data were then analyzed by SPSS 18 with Two-Way ANOVA and Tukey HSD.

Result: There were differences in postprandial glucose levels in people with diabetes who obtained insulin injection at the site of the abdominal, deltoid, thigh and gluteus (P <0.05). There were differences in postprandial glucose levels in people with diabetes who obtained insulin injections at 0, 10, 20 and 30 minutes before meal (P <0.05). The location and the most effective time for insulin injection was in the abdomen at time 0 minute before meal (P <0.05).

Conclusion: Injection of insulin made in the abdomen by the time of meals effectively controlled postprandial glucose levels in patients with diabetes mellitus type 2.


Insulin Injection Site; Time Interval Administration; Postprandial Glucose; Diabetes Type 2

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