Tehran University of Medical Sciences Nursing Practice Today 2383-1154 8 2 2020 11 01 146 154 Carla Sílvia Fernandes Department of Nursing, Nursing School of Porto, Center for Health Technology and Services Research, Porto, Portugal Bruno Magalhães Department of Nursing, Santa Maria Health School, Center for Health Technology and Services Research, Porto, Portugal Célia Santos Department of Nursing, Nursing School of Porto, Center for Health Technology and Services Research, Porto, Portugal Juan Galiano Nursing Department, Andalusian Health Service, University of Jaén, Centro de Investigación Biomédica en Red Epidemiologia y Salud Publica Jaén, Spain 2020 05 20 2020 08 09 Background & Aim: People undergoing chemotherapy treatment of an oncologic disease refer to the need to promote the process of self-management of the disease and the symptoms associated with treatment. This study aims to describe the development protocol of a mobile application to support the self-management of symptoms associated with chemotherapy treatment, the IGestSaúde. Methods & Materials: The research is divided into six stages, using an exploratory/descriptive pilot study conducted over 36 months. The stages include research and fundamentals, development, validation of therapeutic guidelines, field study, technological development, implementation, and mobile application evaluation. Discussion: The project will monitor and improve patients' compliance to chemotherapy, to prevent patients’ complications through preventive indications for self-care, and to improve patients' responses to uncontrolled symptoms or complications. Conclusion: Mobile applications can be considered a viable and effective means for self-management of complications associated with chemotherapy treatment, supported by scientific evidence and these people's specific needs. https://npt.tums.ac.ir/index.php/npt/article/view/1091 https://npt.tums.ac.ir/index.php/npt/article/download/1091/480