Tehran University of Medical Sciences Nursing Practice Today 2383-1154 3 3 2016 10 01 91 98 EN Aeen Mohammadi Department of E-learning in Medical Education, Virtual School, Tehran University of Medical Sciences, Tehran, Iran AND Center of Excellence for E-learning in Medical Education, Tehran University of Medical Sciences, Tehran, Iran Mitra Zolfaghari Department of E-learning in Medical Education, Virtual School, Tehran University of Medical Sciences, Tehran, Iran AND Center of Excellence for E-learning in Medical Education, Tehran University of Medical Sciences, Tehran, Iran AND Nursing & Midwifery Care Research Center, Tehran University of Medical Sciences, Tehran, Iran Masoud Nikfarjam Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran Neda Parvin Medical Plants Research Center, hahrekord University of Medical Sciences, Shahrekord, Iran Najme Shahin Fard Department of E-learning in Medical Education, Virtual School, Tehran University of Medical Sciences, Tehran, Iran. ANDMedical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran 2016 07 10 2017 01 01 Background & Aim: Lack of adherence to prescribed medication is a main concern in medicine especially in chronic diseases. The aim of present study was to determine the effect of supportive text message on the adherence to treatment of depression. Methods & Materials: This quasi-experimental study was conducted on sixty eligible patients with diagnosis of depression who referred to a psychiatry clinic in Shahrekord. The patients were allocated to supportive text message and control groups. The patients in both groups were treated with the same antidepressants; however, the patients in supportive text message group additionally received daily text messages for six weeks. The adherence to medication was assessed by a researcher-made questionnaire and the severity of depression was assessed by Beck depression inventory. Results: Immediately after intervention, average score of depression showed a significant improvement in both groups (P<0.001). Moreover, the average score of depression and medication adherence, in two groups (supportive short message and control group) had no significant differences (16.76 ± 4.70 and 63.3% Vs 19.83 ± 7.39 and 53.3%) (P= 0.06 and 0.31). Conclusion: Daily supportive text message in this study could not improve antidepressant adherence and depressive symptoms in patients with major depression. https://npt.tums.ac.ir/index.php/npt/article/view/145 https://npt.tums.ac.ir/index.php/npt/article/download/145/143