Tehran University of Medical Sciences Nursing Practice Today 2383-1154 10 4 2023 10 18 327 343 Skarlet Vásquez Nursing Program, Health Sciences Faculty, Autonomous University of Bucaramanga, Bucaramanga, Colombia Olga Cortés Research Center, Fundación Cardioinfantil-Instituto de Cardiología, Bogotá, Colombia María Paipa-Campos Department of Nursing, Fundación Cardioinfantil-Instituto de Cardiología, Bogotá, Colombia Carolina Mójica-Diaz Research Center, Fundación Cardioinfantil-Instituto de Cardiología, Bogotá, Colombia Yudy Andrea Rojas-Castañeda Department of Nursing, Fundación Cardioinfantil-Instituto de Cardiología, Bogotá, Colombia Sandra Patricia Pulido-Barragán Department of Nursing, La Samaritana University Hospital, Bogotá, Colombia Martha Cecilia Arias-Portillo Department of Nursing, La Samaritana University Hospital, Bogotá, Colombia Maribel Esparza-Bohorquez Department of Nursing, Santander Ophthalmology Foundation- FOSCAL, Bucaramanga, Colombia Natalia Martínez Department of Nursing, Santander Ophthalmology Foundation- FOSCAL, Bucaramanga, Colombia Indira Alba Arévalo-Sandoval Department of Nursing, University Clinic of Sabana, Bogotá, Colombia 2023 03 22 2023 09 19 Background & Aim: Clinical recommendations for ventilation management in patients with COVID-19 acute respiratory distress syndrome suggest the use of the prone position as a complementary therapy, however, there is wide variability in its use. The purpose of this study is to identify the predictor factors for using the prone position for patients hospitalized in intensive care units with COVID-19 acute respiratory distress syndrome. Methods & Materials: A Cross-sectional study was carried out, including adult patients with COVID-19 acute respiratory distress syndrome hospitalized in intensive care units of four hospitals in Colombia. A multiple logistic regression model was constructed in which the main outcome was the prone position in intensive care, and the independent variables included sociodemographic characteristics, history, health status, progress, and treatment. Results: A total of 473 patients were included in this study; 59.8% (n=283) received prone position therapy within 24-96 hours of hospitalization in intensive care. Out of the total of eligible variables in the logistics-regression model, factors in favor of the prone position were PCR>10mg/L (OR=3.33), private healthcare network (OR=1.99), hypertension (OR=1,76), cough or dyspnea symptoms at intensive care admission (OR=2.69 and OR=1.91), oxygen saturation <90% (OR=1.84). Factors against the prone position were heart disease (OR=0.34), FiO2>50% (OR=0.32), and TP>13 seconds (OR=0.53). Conclusion: Patients with COVID-19 acute respiratory distress syndrome with a higher probability of prone position in intensive care were those with PCR>10mg/L, cough, dyspnea, and private healthcare network. The predictors identified in this study could help standardize the prone position therapy. https://npt.tums.ac.ir/index.php/npt/article/view/2438 https://npt.tums.ac.ir/index.php/npt/article/download/2438/592