Tehran University of Medical Sciences Nursing Practice Today 2383-1154 11 3 2024 07 08 272 282 Khatereh Salavati Department of Nursing, Faculty of Nursing and Midwifery, Shahed University, Tehran, Iran Nahid Rejeh Elderly Care Research Center, Department of Nursing, Faculty of Nursing and Midwifery, Shahed University, Tehran, Iran Farhad Rohani Department of Geriatric Health and Psychiatric Nursing, Faculty of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran Alireza Dehghan Nayeri Cardiologist, Cardiovascular Research Center, Alborz University of Medical Sciences, Karaj, Iran 2024 02 07 2024 07 02 Background & Aim: Patients who receive percutaneous coronary interventions often display inadequate levels of self-care actions, which could create difficulties in managing the disease and achieving favorable treatment results. This study investigates the impact of using an educational mobile application on self-care behaviors in patients undergoing percutaneous coronary intervention. Methods & Materials:  A randomized clinical trial was conducted with 110 patients undergoing percutaneous coronary interventions at Shahid Rajaei Hospital in Karaj, Iran, in 2023. The study enrolled and assigned them to either the intervention group (n=55) or the control group (n=55) by block randomization. In addition to training upon discharge, the experimental group received educational resources via a mobile phone application. The data collection instruments included MSCBS. Patients completed the MSCBS before the intervention and 4 weeks later. The data were analyzed with SPSS 21. The study's level of significance was set to P<0.05. Results: Before the intervention, there was no significant difference in the self-care scores and the subscales between the two groups (P<0.05). Nonetheless, After the intervention, a significant difference was observed in the self-care scores and the subscales between the control and intervention groups, (p=0.001), and the difference in scores between the control and intervention groups increased significantly after the intervention and the scores of the intervention group had a significant increase compared to the scores of the control group. Conclusion: The study showed that the mobile phone educational application could improve self-care behaviors in patients undergoing percutaneous coronary interventions. Therefore, it can be recommended that nurses working in medical centers use this educational application to enhance self-care in these patients. https://npt.tums.ac.ir/index.php/npt/article/view/3010 https://npt.tums.ac.ir/index.php/npt/article/download/3010/624