Tehran University of Medical Sciences Nursing Practice Today 2383-1154 12 3 2025 02 17 259 274 İsmail Toygar Fethiye Faculty of Health Sciences, Muğla Sıtkı Koçman University, Muğla, Turkey Gülcan Bağçivan School of Nursing, İstanbul, Koç University, Turkey AND College of Nursing and Health Sciences, University of Massachusetts Dartmouth, North Dartmouth, Massachusetts, USA Ayşe Arıkan Dönmez Nursing Faculty, Hacettepe University, Ankara, Turkey Furkan Bilek Fethiye Faculty of Health Sciences, Muğla Sıtkı Koçman University, Muğla, Turkey Çiğdem Fulya Dönmez Fethiye Faculty of Health Sciences, Muğla Sıtkı Koçman University, Muğla, Turkey AND School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, Scotland, UK Pınar Borman Faculty of Medicine, Ankara Medipol University, Ankara, Turkey Mehmet Çalışır Faculty of Architecture and Engineering, Recep Tayyip Erdoğan University, Rize, Turkey Yasin Karan Faculty of Architecture and Engineering, Recep Tayyip Erdoğan University, Rize, Turkey Elif Deniz Kaçmaz Bakırçay University, Faculty of Health Sciences, Nursing Department, İzmir, Turkey 2024 10 16 2024 12 18 Background & Aim: Early detection of lymphedema is crucial to prevent progression to advanced stages that impair the quality of life in breast cancer survivors. This study aims to develop and evaluate LYMPH-V, a wearable arm volume measurement device and mobile application designed for the prevention and early detection of breast cancer-related lymphedema. Methods & Materials: The study consists of two phases. In the first phase, the LYMPH-V wearable device and a supportive mobile application will be developed. The app will feature five core components: exercise modules, educational content, coping strategies, arm volume measurement/recording, and personalized reminders. Content will be created based on current guidelines and expert opinions. In the second phase, the effectiveness of the intervention will be assessed through a pilot randomized controlled trial, a reproducibility study, and usability evaluations. The device uses stretch sensors to monitor arm volume, and the mobile app provides alerts if measurements suggest early signs of lymphedema. Data will be stored securely and shared with healthcare professionals upon user approval. Results: Expected outcomes include high usability, strong agreement with manual measurements, and improved capacity for at-home lymphedema monitoring and prevention. Conclusion: LYMPH-V offers a promising digital solution that empowers survivors and healthcare providers through home-based arm volume tracking. This approach may facilitate early intervention, reduce healthcare burden, and enhance quality of life for breast cancer survivors. https://npt.tums.ac.ir/index.php/npt/article/view/3578 https://npt.tums.ac.ir/index.php/npt/article/download/3578/660