Tehran University of Medical Sciences Nursing Practice Today 2383-1154 0 0 2026 10 06 5479 5479 Said Mubarak Said Alhakmani School of Nursing, College of Health Sciences, University of Nizwa, Nizwa, Oman Maryam Rassouli School of Nursing, College of Health Sciences, University of Nizwa, Nizwa, Oman Hadis Ashrafizadeh School of Nursing, Dezful University of Medical Sciences, Dezful, Iran Oscar Maramg Turringan School of Nursing, College of Health Sciences, University of Nizwa, Nizwa, Oman Salem Said Al Touby School of Nursing, College of Health Sciences, University of Nizwa, Nizwa, Oman 2026 07 25 2026 09 21 Background & Aim: Providing comprehensive, holistic care is a fundamental goal of healthcare systems, and palliative care constitutes an essential component of such care. Nurses' and physicians' attitudes may influence the integration of palliative care into routine clinical practice. This study aimed to characterize nurses' and physicians' knowledge of and attitudes toward palliative care, assess the relationship between these variables, and identify factors independently associated with attitudes in a secondary referral hospital in Oman. Methods & Materials: A cross-sectional descriptive correlational study was conducted among 280 nurses and physicians recruited through convenience sampling from clinical departments at Nizwa Hospital, Oman. Data were collected using a demographic questionnaire and the Health Care Providers' Knowledge and Attitude of Palliative Care Questionnaire. Descriptive statistics, nonparametric tests, Spearman's rank-order correlation, and hierarchical multiple linear regression were performed using IBM SPSS Statistics version 26.0. Results: The mean attitude and knowledge scores were 140.20 ± 13.47 and 18.60 ± 4.11, respectively. Knowledge and attitude scores showed a statistically significant, positive, moderate correlation (rₛ = 0.348, p < 0.001). In the final hierarchical regression model, higher knowledge scores were independently associated with higher attitude scores (β = 0.353, p < 0.001), and the model accounted for 21.0% of the variance in attitude scores. Conclusion: Knowledge was positively and moderately associated with attitudes toward palliative care, and this association persisted after adjustment for the examined variables. These findings may inform educational planning at the study hospital; however, given the cross-sectional design, they do not establish that higher knowledge leads to more favorable attitudes or improved quality of care. The effectiveness of educational programs should be evaluated in intervention studies. https://npt.tums.ac.ir/index.php/npt/article/view/5479