The effect of vaginal evening primrose on the Bishop score of term nulliparous women
,
Abstract
Background & Aim: Desirable bishop score is necessary for having a successful delivery. Prostaglandins are effective on cervical ripening and primrose contains precursors of these materials. Therefore, the present study was conducted to evaluate the effect of vaginal Evening primrose on the bishop score among term nulliparous women.
Methods & Materials: The present double-blind randomized clinical trial was conducted on 86 nulliparous women who referred to the comprehensive health service centers of Rafsanjan from November 2017 to May 2018. The samples were selected through convenient sampling method and allocated into two intervention and placebo groups with simple random assignment. The intervention group used a daily dose of 1000 mg vaginal capsules of Evening primrose from the 38th week of pregnancy until delivery and the placebo group received similar placebo with similar administration method. The Information about the women’s bishop score was gathered from the participants’ medical files in the hospital and then was analyzed using SPSS software version 16 and Kolmogorov-Smirnov test, Chi-square test and independent t-test.
Results: The total mean and standard deviation of the bishop score in the intervention and placebo groups was respectively 7.83 ± 2.09 and 4.46 ± 2.39 and the simplified bishop score in the intervention and the control groups was respectively 5.93 ± 2.42 and 2.81 ± 2.02. The difference between the two groups considering both of the bishop scores was statistically significant (p = 0.001).
Conclusion: Vaginal Evening primrose is effective to ripen the cervix of term nulliparous women and so, it could be administered for this purpose.
2. American College of Obstetricians and Gynecologists. ACOG practice bulletin no. 107: induction of labor. Obstet Gynecol. 2009;114:386-97.
3. Hadi H. Cervical ripening and labor induction: clinical guidelines. Clinical Obstetrics and Gynecology. 2000 Sep 1;43(3):524-36.
4. Baacke KA, Edwards RK. Preinduction cervical assessment. Clinical obstetrics and gynecology. 2006 Sep 1;49(3):564-72.
5. Hofmeyr GJ. Induction of labour with an unfavourable cervix. Best Practice & Research Clinical Obstetrics & Gynaecology. 2003 Oct 1;17(5):777-94.
6. Crane JM. Factors predicting labor induction success: a critical analysis. Clinical obstetrics and gynecology. 2006 Sep 1;49(3):573-84.
7. Teixeira C, Lunet N, Rodrigues T, Barros H. The Bishop Score as a determinant of labour induction success: a systematic review and meta-analysis. Archives of gynecology and obstetrics. 2012 Sep 1;286(3):739-53.
8. Sciscione AC, Muench M, Pollock M, Jenkins TM, Tildon-Burton J, Colmorgen GH. Transcervical Foley catheter for preinduction cervical ripening in an outpatient versus inpatient setting. Obstetrics & Gynecology. 2001 Nov 1;98(5):751-6.
9. Mohammadinia N, Rezaei MA, Loripour M, Heydari N. The effect of consumption of Sisymbrium-seeds at the end of pregnancy on the rate of cesarean delivery and apgar score. The Iranian Journal of Obstetrics, Gynecology and Infertility. 2012;15(27):8-13.
10. Grobman WA. Is it time for outpatient cervical ripening with prostaglandins?. BJOG: An International Journal of Obstetrics & Gynaecology. 2015 Jan;122(1):105.
11. Skouteris H, Wertheim EH, Rallis S, Paxton SJ, Kelly L, Milgrom J. Use of complementary and alternative medicines by a sample of Australian women during pregnancy. Australian and New Zealand Journal of Obstetrics and Gynaecology. 2008 Aug;48(4):384-90.
12. Dowswell T, Kelly AJ, Livio S, Norman JE, Alfirevic Z. Different methods for the induction of labour in outpatient settings. The Cochrane database of systematic reviews. 2010(8):CD007701.
13. Hall HG, McKenna LG, Griffiths DL. Complementary and alternative medicine for induction of labour. Women and Birth. 2012;25(3):142-8.
14. Vahdat M, Tahermanesh K, Kashi AM, Ashouri M, Dodaran MS, Kashanian M, et al. Evening primrose oil effect on the ease of cervical ripening and dilatation before operative hysteroscopy. Thrita. 2015;4(3).
15. Dugoua J-J. Herbal medicines and pregnancy. J Popul Ther Clin Pharmacol. 2010;17(3):e370-e8.
16. Kalati M, Kashanian M, Jahdi F, Naseri M, Haghani H, Sheikhansari N. Evening primrose oil and labour, is it effective? A randomised clinical trial. Journal of Obstetrics and Gynaecology. 2018:1-5.
17. Birch A, Fenner G, Watkins R, Boyd L. Antioxidant properties of evening primrose seed extracts. Journal of agricultural and food chemistry. 2001;49(9):4502-7.
18. Rezapour-Firouzi S, Arefhosseini SR, Mehdi F, Mehrangiz EM, Baradaran B, Sadeghihokmabad E, Mostafaei S, Fazljou SM, Torbati MA, Sanaie S, Zamani F. Immunomodulatory and therapeutic effects of Hot-nature diet and co-supplemented hemp seed, evening primrose oils intervention in multiple sclerosis patients. Complementary therapies in medicine. 2013 ;21(5):473-80.
19. Wing DA, Sheibani L. Pharmacotherapy options for labor induction. Expert opinion on pharmacotherapy. 2015;16(11):1657-68.
20. Girlie VB. The efficacy of evening primrose oil as a cervical ripening agent for gynecologic procedures: A single-blinded, randomized controlled trial. Philippine Journal of Obstetrics and Gynecology. 2015 Jan;39(1):25-8.
21. Shahali S, Khatami F, Abbaspoor Z, Gheraghian B. The effect of vaginal evening primrose capsule on cervical ripening in nulliparous women with post-term pregnancy: A clinical trial. The Iranian Journal of Obstetrics, Gynecology and Infertility. 2018;21(8):30-8.
22. Saberi F, Abedzadeh M, Saadat Z. The use of castor oil on cervical ripening in pregnancies. Journal of Mazandaran University of Medical Sciences. 2008;18(63):11-9.
23. Ivars J, Garabedian C, Devos P, Therby D, Carlier S, Deruelle P, Subtil D. Simplified Bishop score including parity predicts successful induction of labor. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2016; 203:309-14.
24. Ty-Torredes KA. The effect of oral evening primrose oil on bishop score and cervical length among term gravidas. American Journal of Obstetrics & Gynecology. 2006;195(6):S30.
25. Aquino, P.A., Fernandez, H.D., Garcia, M.I., Barrientos, M.A., Apepe, E.T.B. and Pichay, R.L., 2011. Determining the Ease of Cervical Dilation in Patients Given Evening Primrose Oil (Eveprim®) Intravaginally before Hysteroscopy in Postmenopausal and Nulliparous, Premenopausal Women Ages 37-77 Years Old: A Pilot Study. Journal of Minimally Invasive Gynecology, 18(6), pp.S126-S127.
26. Nordeng H, Havnen GC. Impact of socio-demographic factors, knowledge and attitude on the use of herbal drugs in pregnancy. Acta obstetricia et gynecologica Scandinavica. 2005;84(1):26-33.
27. Hosseini SH, Rajabzadeh R, Nosrati H, Naseri F, Toroski M, Mohaddes Hakkak H, et al. Prevalence of medicinal herbs consumption in pregnant women referring to Bojnurd health care centers. The Iranian Journal of Obstetrics, Gynecology and Infertility. 2017;20(9):33-40.
28. Momeni H, Salehi A, Seraji A. The comparison of Vitex agnus castus and evening primrose oil on women’s depression: a clinical trial. Yafte. 2013;15(2):67-76.
29. Nonette DN. The effectiveness of evening primrose oil gel capsule as a cervical ripening agent during labor induction as measured by bishop score on term singleton pregnant patients. Philippine Journal of Obstetrics and Gynecology. 2017;41(2):1-4.
| Files | ||
| Issue | Vol 6 No 4 (2019): Autumn | |
| Section | Original Article(s) | |
| DOI | https://doi.org/10.18502/npt.v6i4.1942 | |
| Keywords | ||
| evening primrose vaginal cervical ripening bishop score nulliparous | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
